남한에 거주하는 북한 이주민 여성의 갑상선기능 이상:무증상 갑상선기능저하증을 중심으로
Thyroid Dysfunction of North Korean Women Living in South Korea, Focusing on Subclinical Hypothyroidism
- 발행
- 2012
- 소속·발행
- 고려대학교
- 출처
- 국내 KCI
- UCI
- G704+INS000001031-ART001695956
- 원문등록
- 2012-09-25
- 원문
- 원문 보기 ↗
개념
키워드
North Korean refugees, Subclinical hypothyroidism, Thyroid autoantibody, North Korean refugees, Subclinical hypothyroidism, Thyroid autoantibody
초록
Background: Thyroid function depends on ethnic and environmental factors. North Korean refugees have the same genetic background as South Koreans, but they have been exposed to different environments. This study examines the prevalence and pattern of thyroid disorders in North Korean women living in South Korea, focusing on subclinical hypothyroidism (SCH).
 Methods: The intended sample was a total of 327 North Korean women residing in Seoul. Health questionnaires and medical examinations,including serum thyrotropin (thyroid stimulating hormone, TSH), free thyroxine, and thyroid autoantibodies, were conducted.
 Results: The prevalence of SCH was 9.4%. In logistic regression analysis, smoking, menopause, length of stay in South Korea, body mass index, history of thyroid disease, and metabolic syndrome were not associated with the risk of SCH. Whereas, the positivity of autoantibodies were associated with a high risk for SCH (odds ratio [OR], 4.840; 95% confidence interval [CI], 1.80-13.017; P = 0.002),and age was associated with a low risk for SCH (OR, 0.94; 95% CI, 0.888-0.994; P = 0.031). The serum TSH levels also decreased with increasing age, and in particular, there w